The Ghostbusters are all confined to bed with an illness, so they put Slimer in charge of the firehouse.

A mouse appears in the firehouse, and Slimer must help the poor little rodent survive by thwarting all of Manx's efforts to exterminate his new friend.

Rudy begins a messenger service, and Slimer becomes Rudy's driver, unaware that Professor Dweeb is plotting again.

Fred receives an invitation from Slimer to join the gang at the firehouse for a barbecue, but Morris Grout has hired Bruiser, guard dog extraordinaire.

After Peter complains to him about the cost of food, Slimer looks for a job so he can help out.

Luigi asks Slimer to deliver a lavish spread for a party being held at Rafael's house, but Manx desires the food.

Believing he will get rich quick, Rudy hustles a job as a gardener at a ritzy mansion and cons Slimer into joining him.

While shopping for a birthday gift for Chilly, Slimer has to endure a running conflict with Bruiser.

Rudy sees an organ grinder with a monkey and gets the bright idea to go into business for himself, employing a certain green ghost.

When Slimer saves a helpless baby pigeon being pursued by a hungry Manx he finds his troubles are only just beginning.

After enjoying a concert, Slimer is inspired to hold a concert of his own, but must evade the clutches of Professor Dweeb and Elizabeth.

Slimer befriends a small, extraterrestrial who lands on the firehouse roof.

Slimer plans to build a clubhouse for himself on the firehouse roof, but Manx has other ideas.

Slimer and Chilly go camping and run into a pair of pesky rabbits that attempt to raid the food supply.

Slimer becomes a detective and stumbles upon a plan devised by the evil Dr. Strangedog... who is being aided and abetted by Bruiser.

Slimer discovers that the Junior Ghostbusters have left behind some papers for school and tries to return them.

At the movies, Slimer is pursued by Dweeb, causing the green ghost to enter the film and encounter the deadly Squid Monster.

Peter, believing Slimer is watching too much television, reads him a book, but soon the story begins to take on its own slime-like quality.

Bud takes Slimer and Fred to the beach and must prevent Bruiser from spoiling Fred's fun.

When his trip to the amusement park is cancelled due to a storm, Slimer uses his imagination and his drawing skills to pass the time.

When Manx, with false bandages and phony limp, cons Janine for sympathy, Slimer attempts to unmask his scheme.

Fred attends a one-day Obedience School, but soon discovers that the place is like a military boot camp, run by Bruiser.

Slimer is inspired to increase business at Luigi's restaurant, but Manx attempts to thwart their efforts by destroying their massive pizza.

Through Slimer's vivid imagination, "Jack And The Beanstalk" becomes very personalized.

Slimer and Fred enter a dog show in an effort to win food, competing against Dweeb and Elizabeth.

At the firehouse Slimer attempts to wallpaper the kitchen in an effort to please the Ghostbusters, but Dweeb and Elizabeth are intent on stopping and capturing him.

Two spacemen mistaking Slimer for a typical earthling capture him and take him to their home!

A monstrous ghost housed in the Containment Unit manages to free himself, prompting a frantic Slimer to enlist the help of the Junior Ghostbusters.

In an attempt to make life simpler at the Hotel Sedgewick, Slimer, Fred and Bud manage to get Grout transferred to a ritzy, uptown hotel, but soon madness reigns as Professor Dweeb becomes the new manager.

The Sedgewick Hotel gets more than it bargained for when Goolem and Zugg arrive, prompting Slimer to disguise himself as Scareface.

Goolem and Zugg return to New York seeking revenge against Slimer and are successful in stopping the Ghostbusters with a sleeping spell.

On Halloween Slimer and Fred head out to collect bags of goodies, but unbeknownst to them, Professor Dweeb teams up with Goolem and Zugg in a plan to get rid of Slimer.